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Systemic inflammation driven by diet and gut microbiome imbalance can worsen nerve pain, slow tissue healing, and reduce the effectiveness of regenerative therapies

However, if you've had neurological symptoms from long-standing deficiency, patience is key - it may take several months to see significant improvement as your nervous system heals

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Why It Pairs So Well With GLP-1 Agonists GLP-1 agonists like Retatrutide create a caloric deficit through multiple routes: appetite suppression, slowed gastric emptying, and (in Reta's case) glucagon receptor agonism that drives additional energy expenditure

Peptides can interact and degrade when mixed, potentially reducing or eliminating their effectiveness